Walking the Isobole of Drug Interaction

NACompletedINTERVENTIONAL
Enrollment

87

Participants

Timeline

Start Date

February 28, 2014

Primary Completion Date

September 30, 2015

Study Completion Date

September 30, 2015

Conditions
Hemodynamic InstabilityDisorder of Oxygen TransportInteractionAnesthesia
Interventions
DRUG

Group A propofol + remifentanil

Predicted TOL90% according to Bouillon model

DRUG

Group B propofol + remifentanil

TOL 90% according to the Bouillon interaction model

DRUG

Group C propofol + remifentanil

TOL 90% according to the Bouillon interaction model

DRUG

group D propofol + remifentanil

TOL 90% according to the Bouillon interaction model

Trial Locations (1)

9713EZ

University Medical Center Groningen, Groningen

All Listed Sponsors
lead

University Medical Center Groningen

OTHER

NCT02067936 - Walking the Isobole of Drug Interaction | Biotech Hunter | Biotech Hunter