20
Participants
Start Date
February 28, 2014
Primary Completion Date
October 31, 2015
Study Completion Date
November 30, 2015
Standard Chelation
This will comprise of standard chelation drugs (Deferasirox or Deferoxamine or Combination of Deferoxamine and Deferiprone).The dosage and drug used will depend on ferritin levels and individual requirement, as determined by the treating hematologist and will be in accordance with the Iron chelation guidelines from Pakistan Thalassemia Society.
Amlodipine
doses of 0.2 to 0.25 mg/kg/day PO would be given during this trial
Aga Khan University Hospital, Karachi
Aga Khan University
OTHER