Study Of Tasquinimod In Asian Chemo-Naïve Patients With Metastatic Castrate-Resistant Prostate Cancer

PHASE3TerminatedINTERVENTIONAL
Enrollment

146

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

May 31, 2015

Study Completion Date

May 31, 2015

Conditions
Prostatic Neoplasms, Castration-Resistant
Interventions
DRUG

Tasquinimod

A patient initially received a 0.25 mg/day dose which was then titrated through 0.5 mg/day (from Day 15) to a maximum of 1 mg/day (from Day 29). If tolerability issues arose at 0.5 or 1 mg/day, patients had their dose reduced to 0.25 or 0.5 mg/day, respectively.

DRUG

Placebo

Placebo capsules were identical to tasquinimod capsules in appearance and excipients but excluded the active compound (tasquinimod).

Trial Locations (36)

10002

National Taiwan University Hospital, Taipei

11217

Taipei Veterans General Hospital, Taipei

40447

China Medical University Hospital, Taichung

40705

Taichung Veterans General Hospital, Taichung

61004

West China Hospital Sichuan University, Chengdu

100020

Beijing Chao-Yang Hospital Capital Medical University, Beijing

100034

Peking University First Hospital, Beijing

100044

Peking University People's Hospital, Beijing

100050

Beijing Friendship Hospital Capital Medical University, Beijing

100191

Peking University Third Hospital, Beijing

100370

Peking Union Medical College Hospital, Beijing

100730

Beijing Hospital of Ministry of Health, Beijing

200025

Ruijin Hospital Shanghai Jiaotong University of Medicine, Shanghai

200032

Fudan University Shanghai Cancer Center, Shanghai

Zhongshan Hospital Fudan University, Shanghai

200040

Huadong Hospital Fudan University, Shanghai

Huashan Hospital Fudan University, Shanghai

200072

Shanghai Tenth People's Hospital, Shanghai

200092

Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai

210009

Jiangsu Cancer Hospital, Nanjing

215004

The Second Affiliated Hospital of Soochow University, Suzhou

300060

Tianjin Medical University Cancer Institute and Hospital, Tianjin

310003

The First Affiliated Hospital College of Medicine Zhujiang University, Hangzhou

325000

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou

330006

The First Affiliated Hospital of Nanchang University, Nanchang

400038

Southwest Hospital (the First Affiliated Hospital of Third Military Medical University PLA), Chongqing

430030

Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan

510000

Sun Yat-sen University Cancer Center, Guangzhou

510180

Guangshou First People's Hospital, Guangzhou

610072

Sichuan Academy of Sichuan Medical Sciences & Sichuan Provincial People's Hospital, Chengdu

610083

General Hospital Chengdu Military Region of PLA, Chengdu

361-711

Chungbuk National University Hospital, Cheongju-si

501-757

Chonnam National University Hospital, Gwangju

135-720

Gangnam Severance Hospital, Seoul

137-701

The Catholic University of Korea Seoul St. Mary's Hospital, Seoul

138-736

Asan Medical Center, Seoul

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Ipsen

INDUSTRY