3rd Party LMP1/2-Specific Cytotoxic T Lymphocytes for EBV-Associated Lymphoma

PHASE1CompletedINTERVENTIONAL
Enrollment

1

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

December 31, 2016

Study Completion Date

December 31, 2017

Conditions
Non-Hodgkins LymphomaHodgkins LymphomaLymphoproliferative Disorder
Interventions
DRUG

EBV CTL's

Eligible patients with a matched cell line will be infused with 3rd party CTLs and monitored for adverse events and response. Patients who show a response and tolerate the infusion well may receive up to 5 infusions total 4-6 weeks apart.

OTHER

Peripheral Blood Donor

Donors who are EBV+ and meet the eligibility criteria will be consented to provide 60-120 ml peripheral blood once for future use for this and other clinical trials using 3rd party CTLs.

Trial Locations (2)

10595

New York Medical College, Valhalla

Unknown

Children's National Medical Center, Washington D.C.

All Listed Sponsors
collaborator

Children's National Research Institute

OTHER

collaborator

Baylor College of Medicine

OTHER

collaborator

M.D. Anderson Cancer Center

OTHER

collaborator

University of Michigan

OTHER

collaborator

University of Utah

OTHER

collaborator

City of Hope Medical Center

OTHER

collaborator

Ohio University

OTHER

collaborator

Johns Hopkins University

OTHER

lead

New York Medical College

OTHER