A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

198

Participants

Timeline

Start Date

March 10, 2014

Primary Completion Date

March 15, 2021

Study Completion Date

December 31, 2025

Conditions
Breast Neoplasms
Interventions
DRUG

LY2835219

Administered orally.

DRUG

Letrozole

Administered orally.

DRUG

Anastrozole

Administered orally.

DRUG

Tamoxifen

Administered orally.

DRUG

Exemestane

Administered orally.

DRUG

Everolimus

Administered orally.

DRUG

Trastuzumab

Administered IV infusion.

DRUG

LY3023414

Administered orally.

DRUG

Fulvestrant

Administered IM.

DRUG

Pertuzumab

Administered IV infusion.

DRUG

Loperamide

Administered orally.

DRUG

Endocrine therapy

Endocrine therapy administered orally.

Trial Locations (13)

10032

Columbia University College of Phys & Surgeons, New York

10065

Memorial Sloan Kettering Cancer Center, New York

15213

Univ of Pittsburgh Cancer Inst. (UPCI), Pittsburgh

27514

University of North Carolina at Chapel Hill, Chapel Hill

37203

Peggy and Charles Stephenson Oklahoma Cancer Center, Nashville

Tennessee Oncology PLLC, Nashville

72758

Highlands Oncology Group - Duplicate 2, Rogers

97213

Providence Cancer Center Oncology Hematology Care, Portland

92037-0845

University of California - San Diego, La Jolla

02215

Dana Farber Cancer Institute, Boston

55905-0002

Mayo Clinic, Rochester

37232-6307

Vanderbilt University Medical Center, Nashville

78229-3307

South Texas Accelerated Research Therapeutics (START), San Antonio

All Listed Sponsors
lead

Eli Lilly and Company

INDUSTRY