NCT02049268 - Neural Mechanisms Underlying Nicotine and Alcohol Combinations | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

July 31, 2013

Primary Completion Date

December 31, 2015

Study Completion Date

December 31, 2015

Conditions

Focus: Effects of Nicotine and Alcohol on Brain Circuits

Interventions

DRUG

Nicotine + Alcohol

14 mg nicotine patch applied in combination with vodka and orange juice alcoholic beverage (to reach blood alcohol level (BAL) = 0.08 based on subject weight, which is approximately 2-3 drinks for 400 mL volume)

DRUG

Placebo Nicotine + Alcohol

Placebo nicotine patch applied in combination with vodka and orange juice alcoholic beverage (to reach BAL = 0.08 based on subject weight, which is approximately 2-3 drinks for 400 mL volume)

DRUG

Nicotine + Placebo Alcohol

14 mg nicotine patch applied in combination with 400 mL orange juice beverage with a trace of alcohol to create placebo alcohol mixture.

Trial Locations (1)

02478

McLean Hospital, Belmont

All Listed Sponsors

lead

Mclean Hospital

OTHER