Dose-finding of Rivaroxaban in Hemodialysis

PHASE4CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

September 30, 2013

Primary Completion Date

February 28, 2014

Study Completion Date

October 31, 2014

Conditions
Chronic Renal Failure
Interventions
DRUG

Rivaroxaban 10 mg

"Measurement of AUC of rivaroxaban and effect on coagulation assays:~Venous blood samples (8.5 ml) are collected immediately before (t=0) and at t= 0,5, 1, 2, 4, 8, 12, 24, 36 and 44 hours after administration of rivaroxaban.~Effect of dialysis on levels of rivaroxaban:~Venous blood samples (8.5 ml) are collected at the start of dialysis (t=0) and at t=1, 2, 3 and 4 hours."

Trial Locations (2)

8000

AZ Sint-Jan Brugge-Oostende AV, Bruges

9300

OLV Aalst, Aalst

All Listed Sponsors
collaborator

Onze Lieve Vrouw Hospital

OTHER

lead

AZ Sint-Jan AV

OTHER

NCT02047006 - Dose-finding of Rivaroxaban in Hemodialysis | Biotech Hunter | Biotech Hunter