Steroid Use in Pediatric Fluid and Vasoactive Infusion Dependent Shock - Pilot Study

PHASE4CompletedINTERVENTIONAL
Enrollment

57

Participants

Timeline

Start Date

July 31, 2014

Primary Completion Date

April 30, 2016

Study Completion Date

April 30, 2016

Conditions
Shock
Interventions
DRUG

Hydrocortisone

Hydrocortisone will be made up as a 10 mg/ml solution so the volume of added fluid will be very small (2 to 10 mls even for the initial dose of 2 mg/kg).

OTHER

Placebo

The placebo (normal saline) will be identical in appearance, volume and smell to the active study drug (hydrocortisone).

Trial Locations (7)

T3B 6A8

Alberta Children's Hospital, Calgary

V6H 3V4

British Columbia Children's Hospital, Vancouver

B3K 6R8

IWK Health Centre, Halifax

L8N 3Z5

McMaster Children's Hospital, Hamilton

K1H8L1

Children's Hospital of Eastern Ontario, Ottawa

H3H 1P3

Montreal Children's Hospital of the MUHC, Montreal

H3T 1C5

Hospital St. Justine, Montreal

All Listed Sponsors
lead

Children's Hospital of Eastern Ontario

OTHER

collaborator

Alberta Children's Hospital

OTHER

collaborator

British Columbia Children's Hospital

OTHER

collaborator

London Health Sciences Centre

OTHER

collaborator

St. Justine's Hospital

OTHER

collaborator

IWK Health Centre

OTHER

collaborator

Montreal Children's Hospital of the MUHC

OTHER