Phase 2 Study Assessing Efficacy and Safety of Crizotinib in Patients Harboring an Alteration on ALK, MET or ROS1

PHASE2CompletedINTERVENTIONAL
Enrollment

246

Participants

Timeline

Start Date

August 31, 2013

Primary Completion Date

June 30, 2019

Study Completion Date

December 6, 2023

Conditions
Hematologic CancersSolid TumorsMetastatic Cancer
Interventions
DRUG

Crizotinib

"Patients will receive oral crizotinib, daily continuously, until progression or unacceptable toxicity develops.~-250 mg twice daily for adults ≥ 18 years of age~* 280 mg/m² twice daily for children and adolescents aged from 1 to 17 (except ALCL).~* 165 mg/m² twice daily for ALCL patients aged from 1 to 17."

Trial Locations (1)

94805

Gustave Roussy, Villejuif

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Cancer Institute, France

OTHER_GOV

collaborator

Fondation ARC

OTHER

collaborator

Pfizer

INDUSTRY

lead

UNICANCER

OTHER

NCT02034981 - Phase 2 Study Assessing Efficacy and Safety of Crizotinib in Patients Harboring an Alteration on ALK, MET or ROS1 | Biotech Hunter | Biotech Hunter