A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers

CompletedOBSERVATIONAL
Enrollment

77

Participants

Timeline

Start Date

October 31, 2013

Primary Completion Date

May 31, 2015

Study Completion Date

May 31, 2015

Conditions
Lupus Erythematosus, CutaneousLupus Erythematosus, SystemicLupus Erythematosus, DiscoidHealthy
Interventions
PROCEDURE

Skin biopsy

Participants with LE will have 2 adjacent 4 mm punch biopsies collected from involved and uninvolved skin at one timepoint and again from the involved skin site approximately 12 weeks later. Healthy participants will have 2 adjacent 4 mm punch biopsies taken at one timepoint.

PROCEDURE

Blood collection

Blood for serum analyses will be taken from all participants. Blood for DNA analysis will only be taken from participants who consent to this separately.

PROCEDURE

Urine collection

Urine will be collected from all participants.

Trial Locations (21)

Unknown

La Jolla

Chicago

Boston

Lansing

Neptune City

Charlotte

Duncansville

Philadelphia

Salt Lake City

Berlin

Kiel

Chihuahua City

Jalisco

Mexico City

Gdansk

Krakow

Wroclaw

Taichung

Taipei

Leeds

London

All Listed Sponsors
lead

Janssen Research & Development, LLC

INDUSTRY

NCT02034344 - A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers | Biotech Hunter | Biotech Hunter