Randomized Controlled Study on Optimize Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

556

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

December 31, 2020

Study Completion Date

December 31, 2025

Conditions
Advanced Rectal Cancer
Interventions
DRUG

Induction chemotherapy, Chemoradiotherapy and gap chemotherapy (Capecitabine combine with oxaliplatin)

All rectal cancer patients in this group will receive induction, gap chemotherapy (capecitabine combined with oxaliplatin) alone with chemoradiotherapy (capecitabine combine with oxaliplatin) before surgery.

RADIATION

standard chemoradiotherapy

All rectal patients in this group will receive standard radiotherapy and surgical resection.

Trial Locations (1)

510060

Sun Yat-Sen University Cancer Center, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER