N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

January 16, 2014

Primary Completion Date

December 30, 2023

Study Completion Date

December 30, 2023

Conditions
Neuroblastoma
Interventions
DRUG

DFMO

DRUG

Celecoxib

DRUG

Cyclophosphamide

DRUG

Topotecan

Trial Locations (13)

2031

Sydney Childrens Hospital KCC, Randwick

30322

AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus, Atlanta

48109

C.S Mott Children's Hospital, Ann Arbor

60637

University of Chicago Comer Children's Hospital, Chicago

76104

Cook Children's Medical Center - Fort Worth, Fort Worth

80045

Children Hospital of Colorado, Aurora

94115

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco

98105

Children's Hospital and Regional Medical Center - Seattle, Seattle

90027-0700

Children's Hospital Los Angeles, Los Angeles

02115

Childrens Hospital Boston, Dana-Farber Cancer Institute., Boston

45229-3039

Cincinnati Children's Hospital Medical Center, Cincinnati

19104-4318

Children's Hospital of Philadelphia, Philadelphia

M5G 1X8

Hospital for Sick Children, Toronto

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

New Approaches to Neuroblastoma Therapy Consortium

OTHER

NCT02030964 - N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan | Biotech Hunter | Biotech Hunter