NCT02025452 - Novel Diagnostics and Probiotics to Improve Management of Paediatric Acute Gastroenteritis | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

March 31, 2014

Primary Completion Date

November 30, 2014

Study Completion Date

December 31, 2014

Conditions

Acute Gastroenteritis

Interventions

OTHER

Rapid diagnostic

Specimens from rectal mucosa will be obtained using flocked swabs at enrolment. Those in 'rapid diagnostic' groups will have them tested using multiplex PCR the day of enrolment and participants with treatable pathogens will have antimicrobials provided. Those in 'delayed diagnostic' groups will have the swabs batched at tested at the conclusion of the study, being treated as per standard of care.

DIETARY_SUPPLEMENT

Probiotic

Lactobacillus reuteri suspended in vegetable oil, 5 drops/day (1 x 10e8 CFU) x 2 months

OTHER

Placebo

Identical in appearance to L. reuteri probiotic (same bottle), but simply vegetable oil. Dose is 5 drops/day x 2 months.

Trial Locations (3)

Unknown

Princess Marina Hospital, Gaborone

Scottish Livingstone Hospital, Molepolole

Bamalete Lutheran Hospital, Ramotswa