Regorafenib in Good Performance Status Patients With Newly Diagnosed Metastatic Colorectal Adenocarcinoma

PHASE2CompletedINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

December 10, 2013

Primary Completion Date

August 26, 2025

Study Completion Date

August 26, 2025

Conditions
Metastatic Colorectal Adenocarcinoma
Interventions
DRUG

Regorafenib

All patients that meet the eligibility criteria who have signed informed consent and have enrolled on the trial will be treated with regorafenib, daily 3 weeks on 1 week off for all cycles. Dose will be escalated to 120 mg in week 2 of cycle 1 and all remaining cycles if no excess toxicity is experienced by the patient at the discretion of the treating physician.

Trial Locations (7)

10065

Memorial Sloan Kettering Cancer Center, New York

10591

Memorial Sloan Kettering Cancer Center Sleepy Hollow, Sleepy Hollow

11203

Downstate Medical Center, Brooklyn

11432

Queens Cancer Center of Queens Hospital, Jamaica

11570

Memorial Sloan Kettering Cancer Center at Mercy Medical Center, Rockville Centre

11725

Memorial Sloan Kettering Cancer Center at Commack, Commack

Unknown

Memorial Sloan Kettering Cancer Center at Basking Ridge, Basking Ridge

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bayer

INDUSTRY

collaborator

State University of New York - Downstate Medical Center

OTHER

collaborator

Queens Cancer Center of Queens Hospital

OTHER

lead

Memorial Sloan Kettering Cancer Center

OTHER