18F-DOPA-PET in Planning Surgery in Patients With Gliomas

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

January 22, 2014

Primary Completion Date

October 25, 2019

Study Completion Date

January 10, 2024

Conditions
Malignant GliomaRecurrent Brain Neoplasm
Interventions
PROCEDURE

Biopsy

Undergo image-guided biopsy

PROCEDURE

Computed Tomography

Undergo 18F-DOPA-PET/CT

PROCEDURE

Diffusion Weighted Imaging

Undergo DTI

DRUG

Fluorine F 18 Fluorodopa

Undergo 18F-DOPA-PET/CT

OTHER

Laboratory Biomarker Analysis

Correlative studies

PROCEDURE

Perfusion Magnetic Resonance Imaging

Undergo pMRI

PROCEDURE

Positron Emission Tomography

Undergo 18F-DOPA-PET/CT

PROCEDURE

Therapeutic Conventional Surgery

Undergo stereotactic craniotomy

Trial Locations (1)

55905

Mayo Clinic, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Mayo Clinic

OTHER