Optimising Operational Use of Artemether-lumefantrine Comparing 3 Day Versus 5 Day

PHASE3CompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

November 25, 2013

Primary Completion Date

February 4, 2015

Study Completion Date

March 25, 2015

Conditions
Plasmodium Falciparum Infection
Interventions
DRUG

Artemether-lumefantrine 3 days

One tablet contains 20mg artemether and 120mg lumefantrine. The standard regimen is twice daily for 3 days with a delay of at least 8 hours between the first and second dose. It is dosed by weight categories. One gram of fish oil will be given to half of the participants in the 3 days arm.

DRUG

Artemether-lumefantrine 5 days

One tablet contains 20mg artemether and 120mg lumefantrine. The experiment regimen is twice daily for 5 days with a delay of at least 8 hours between the first and second dose. It is dosed by weight categories. One gram of fish oil will be given to half of the participants in the 5 days arm.

Trial Locations (1)

Unknown

Medical Action Myanmar, Yangon

All Listed Sponsors
lead

University of Oxford

OTHER

NCT02020330 - Optimising Operational Use of Artemether-lumefantrine Comparing 3 Day Versus 5 Day | Biotech Hunter | Biotech Hunter