CYP3A4 Activity and Mineral Homeostasis

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

92

Participants

Timeline

Start Date

June 30, 2014

Primary Completion Date

December 31, 2020

Study Completion Date

December 31, 2020

Conditions
Vitamin D and Calcium Homeostasis
Interventions
DRUG

Rifampin

P450 inducer

DRUG

Clarithromycin

CYP3A4 and Pgp inhibitor in both intestine and liiver

OTHER

Grapefruit Juice

CYP3A4 inhibitor in intestine

OTHER

Placebo

Trial Locations (1)

98195

University of Washington, Seattle

All Listed Sponsors
collaborator

National Institute of General Medical Sciences (NIGMS)

NIH

lead

University of Washington

OTHER

NCT02019875 - CYP3A4 Activity and Mineral Homeostasis | Biotech Hunter | Biotech Hunter