Allo vs Hypomethylating/Best Supportive Care in MDS (BMTCTN1102)

PHASE2CompletedINTERVENTIONAL
Enrollment

384

Participants

Timeline

Start Date

December 16, 2013

Primary Completion Date

October 5, 2021

Study Completion Date

October 5, 2021

Conditions
MDS
Interventions
PROCEDURE

Allogeneic Hematopoietic Cell Transplant

Bone marrow or peripheral blood stem cell transplant.from a fully matched related (6/6) or unrelated (8/8) donor. The specific transplant treatment regimen will be at the discretion of the treating physician but is required to be reduced-intensity.

PROCEDURE

Hypomethylating Therapy / Best Supportive Care

The specific non-transplant treatment regimen will be at the discretion of the treating physician.

Trial Locations (37)

10029

Mount Sinai Hospital, New York

10065

Memorial Sloan-Kettering Cancer Center, New York

14263

Roswell Park Cancer Institute, Buffalo

19104

University of Pennsylvania Cancer Center, Philadelphia

21201

University of Maryland Medical Systems - Greenebaum Cancer Center, Baltimore

21231

Johns Hopkins, Baltimore

23298

Virginia Commonwealth University MCV Hospitals, Richmond

26506

West Virginia University Hospital, Morgantown

27157

Wake Forest University Health Sciences, Winston-Salem

27599

University of North Carolina Hospital at Chapel Hill, Chapel Hill

University of North Carolina, Chapel Hill

27705

Duke University Medical Center, Durham

30322

Emory University, Atlanta

33624

H. Lee Moffitt Cancer Center, Tampa

40536

University of Kentucky, Lexington

43210

Ohio State/Arthur G. James Cancer Hospital, Columbus

44106

University Hospitals of Cleveland/ Case Western, Cleveland

44195

Cleveland Clinic Foundation, Cleveland

45236

Jewish Hospital BMT Program, Cincinnati

48201

Karmanos Cancer Institute/BMT, Detroit

53211

Medical College of Wisconsin, Milwaukee

55905

Mayo Clinic - Rochester, Rochester

63110

Washington University/Barnes Jewish Hospital, St Louis

66160

University of Kansas Hospital, Kansas City

68198

University of Nebraska Medical Center, Omaha

77030

Baylor College of Medicine/The Methodist Hospital, Houston

University of Texas/MD Anderson CRC, Houston

84132

University of Utah Med School, Salt Lake City

91010

City of Hope National Medical Center, Duarte

94305

Stanford Hospital and Clinics, Stanford

98109

Fred Hutchinson Cancer Research Center, Seattle

32610-0277

University of Florida College of Medicine, Gainesville

60637-1470

University of Chicago, Chicago

02115

Dana Farber Cancer Institute/Brigham & Women's, Boston

Dana Farber Cancer Institute/Massachusetts General Hospital, Boston

97239-3098

Oregon Health & Science University, Portland

37232-8210

Vanderbilt University Medical Center, Nashville

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

collaborator

National Cancer Institute (NCI)

NIH

collaborator

Blood and Marrow Transplant Clinical Trials Network

NETWORK

collaborator

National Marrow Donor Program

OTHER

lead

Medical College of Wisconsin

OTHER

NCT02016781 - Allo vs Hypomethylating/Best Supportive Care in MDS (BMTCTN1102) | Biotech Hunter | Biotech Hunter