Single-arm Trial to Evaluate the Biodistribution and Shedding of Talimogene Laherparepvec

PHASE2CompletedINTERVENTIONAL
Enrollment

61

Participants

Timeline

Start Date

April 7, 2014

Primary Completion Date

January 25, 2016

Study Completion Date

April 19, 2018

Conditions
Melanoma
Interventions
DRUG

Talimogene laherparepvec

Talimogene laherparepvec will be administered by intralesion injection at an initial dose of up to 4.0 mL of 10\^6 PFU/mL. The second and subsequent doses will will be up to 4.0 mL 10\^8 PFU/mL. The second dose should be administered 21 days from the initial dose. All subsequent doses should be given every 14 days.

Trial Locations (14)

27157

Research Site, Winston-Salem

33612

Research Site, Tampa

38138

Research Site, Germantown

40202

Research Site, Louisville

46202

Research Site, Indianapolis

55407

Research Site, Minneapolis

55432

Research Site, Fridley

75230

Research Site, Dallas

84112

Research Site, Salt Lake City

87106

Research Site, Albuquerque

08903

Research Site, New Brunswick

T2N 4N2

Research Site, Calgary

T6G 1Z2

Research Site, Edmonton

H3T 1E2

Research Site, Montreal

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Amgen

INDUSTRY