Propranolol Hydrochloride in Treating Patients With Locally Recurrent or Metastatic Solid Tumors That Cannot Be Removed By Surgery

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

1

Participants

Timeline

Start Date

January 21, 2014

Primary Completion Date

June 12, 2015

Study Completion Date

June 12, 2015

Conditions
Male Breast CancerRecurrent MelanomaStage IV Breast CancerStage IV MelanomaStage IV Ovarian Epithelial CancerStage IV Ovarian Germ Cell TumorUnspecified Adult Solid Tumor, Protocol SpecificHepatocellular Carcinoma
Interventions
DRUG

propranolol hydrochloride

Given PO

OTHER

Correlative Studies

"Correlative studies will be conducted using the following materials:~* Plasma derived from peripheral blood.~* Peripheral blood mononuclear cells (PBMC) derived from patient blood~* Tumor tissue obtained at the time of core needle biopsy at the 2 month time point.~* Paraffin-embedded tumor tissue obtained pre-therapy to make the diagnosis of metastatic disease."

Trial Locations (1)

43210

Ohio State University Comprehensive Cancer Center, Columbus

All Listed Sponsors
lead

William Carson

OTHER

NCT02013492 - Propranolol Hydrochloride in Treating Patients With Locally Recurrent or Metastatic Solid Tumors That Cannot Be Removed By Surgery | Biotech Hunter | Biotech Hunter