140
Participants
Start Date
April 30, 2013
Primary Completion Date
April 30, 2018
Study Completion Date
April 30, 2018
bone marrow cells transplantation on collagen scaffold
"120 ml of venous blood will be collected for the platelet gel production. The day of the surgery, 60 ml of bone marrow will be aspirate from the posterior iliac crest and concentrated. a standard ankle arthroscopy will be performed, with the patient in the supine position. The lesion will be detected and cleaned.~An equine collagen type 1 scaffold (IOR-G1, Novagenit, Mezzolombardo, TN, Italy) will be loaded with 2 ml of bone marrow concentrate and cut into an appropriate shape to fit the lesion.~After the scaffold implantation 2 ml of platelet gel will be loaded on the top of implant, in order to provide growth factors and to improve the stability of the implant."
I Clinic, Rizzoli Orthopaedic Institute, Bologna
Istituto Ortopedico Rizzoli
OTHER