"One-step Bone Marrow Mononuclear Cell Transplantation in Talar Osteochondral Lesions"

NACompletedINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

April 30, 2013

Primary Completion Date

April 30, 2018

Study Completion Date

April 30, 2018

Conditions
Osteochondritis
Interventions
PROCEDURE

bone marrow cells transplantation on collagen scaffold

"120 ml of venous blood will be collected for the platelet gel production. The day of the surgery, 60 ml of bone marrow will be aspirate from the posterior iliac crest and concentrated. a standard ankle arthroscopy will be performed, with the patient in the supine position. The lesion will be detected and cleaned.~An equine collagen type 1 scaffold (IOR-G1, Novagenit, Mezzolombardo, TN, Italy) will be loaded with 2 ml of bone marrow concentrate and cut into an appropriate shape to fit the lesion.~After the scaffold implantation 2 ml of platelet gel will be loaded on the top of implant, in order to provide growth factors and to improve the stability of the implant."

Trial Locations (1)

40136

I Clinic, Rizzoli Orthopaedic Institute, Bologna

All Listed Sponsors
lead

Istituto Ortopedico Rizzoli

OTHER

NCT02005861 - "One-step Bone Marrow Mononuclear Cell Transplantation in Talar Osteochondral Lesions" | Biotech Hunter | Biotech Hunter