Linagliptin Inpatient Trial

PHASE4CompletedINTERVENTIONAL
Enrollment

295

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

February 28, 2017

Study Completion Date

March 31, 2017

Conditions
Type 2 Diabetes
Interventions
DRUG

Linagliptin

Linagliptin once daily + correction doses of rapid acting insulin if needed

DRUG

Basal Bolus

Basal bolus regimen with glargine once daily and rapid-acting insulin (lispro or aspart) before meals + + correction doses of rapid acting insulin if needed

DRUG

Linagliptin

Patients with admission A1C \< 7% will be discharged on same pharmacologic regimen (oral agents, insulin therapy) or linagliptin 5 mg/day for 3 months.

DRUG

Linagliptin + 50% Glargine dose on discharge

Patients with admission HbA1c between 7% and 9% will be discharged on previous oral anti-diabetic agents plus linagliptin, and consider glargine insulin at 50% of daily hospital dose for 3 months.

DRUG

Linagliptin + 80% Glargine

Patients with admission HbA1c ≥ 9% will be discharged on previous oral anti-diabetic agents plus linagliptin, and consider glargine insulin at 80% of daily hospital dose for 3 months.

Trial Locations (5)

30322

Emory University Hospital, Atlanta

60612

Rush University Medical Center, Chicago

80220

University of Colorado, Denver

Unknown

Grady Memorial Hospital, Atlanta

02118

Boston Medical Center, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Boston Medical Center

OTHER

collaborator

Rush University

OTHER

collaborator

University of Denver

OTHER

lead

Emory University

OTHER