Phase II Study of Lutetium-177 Labeled Girentuximab in Patients With Advanced Renal Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

August 31, 2011

Primary Completion Date

June 30, 2015

Study Completion Date

June 30, 2015

Conditions
Metastatic Clear Cell Renal Cell Carcinoma
Interventions
DRUG

Lu-177-DOTA-girentuximab

"Drug: In-111-DOTA-girentuximab At day 1, every patient received girentuximab at a dose of 10 mg coupled to DOTA and labeled with 5 mCi of In-111.~Drug: Lu-177-DOTA-girentuximab At day 8-10, every patient receives girentuximab at a dose of 10 mg coupled to DOTA and labeled with 65 mCi/m2 of Lu-177. If eligible, patients are retreated at a dose 75% of the previous dose, for a total of not more than three treatments."

Trial Locations (1)

6500 HB

Radboud University Medical Center, Nijmegen

All Listed Sponsors
lead

Radboud University Medical Center

OTHER

NCT02002312 - Phase II Study of Lutetium-177 Labeled Girentuximab in Patients With Advanced Renal Cancer | Biotech Hunter | Biotech Hunter