Efficacy of Ultrasound-Guided Local Anesthetic Injection Into or Around the Sciatic Nerve for Lower Limb Anesthesia

NACompletedINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

December 31, 2011

Primary Completion Date

September 30, 2012

Study Completion Date

December 31, 2012

Conditions
Orthopedic DisordersFoot DiseasesInjuries, LegInjuries, FootInjuries, Knee
Interventions
PROCEDURE

Intraneural Injection for Subgluteal Sciatic Nerve Block

"The injection will start as the needle penetrates the outermost discernible layer of the nerve (epineurium) under ultrasound guidance. The injection will be adjudicated as intraneural if nerve cross section expansion and a reduction in echogenicity are observed.~Short-axis real-time ultrasound imaging will be used, with an in-plane needle approach."

PROCEDURE

Perineural Injection for Subgluteal Sciatic Nerve Block

"The injection will start as the needle indents the outermost discernible layer of the nerve (epineurium) under ultrasound guidance. The injection will be adjudicated as intraneural if the drug infiltrates the space between the epimysium of the surrounding muscles and the outer epineurium of the sciatic nerve.~Short-axis real-time ultrasound imaging will be used, with an in-plane needle approach."

PROCEDURE

Femoral Nerve Block

Patients will receive an ultrasound-guided femoral nerve block using a short- or long-acting local anesthetic, as deemed indicated.

PROCEDURE

Patient-Controlled Postoperative Analgesia

Patients will receive a patient-controlled intravenous or perineural catheter-based analgesia, depending on their preference and the anesthesiologist's indication.

DRUG

Ropivacaine

Thirty milliliters of 0.75% (wt/vol) ropivacaine will be used for the sciatic nerve block.

Trial Locations (1)

43126

Anesthesia, Critical Care and Pain Medicine - University of Parma, Parma

All Listed Sponsors
lead

University of Parma

OTHER

NCT01999647 - Efficacy of Ultrasound-Guided Local Anesthetic Injection Into or Around the Sciatic Nerve for Lower Limb Anesthesia | Biotech Hunter | Biotech Hunter