54
Participants
Start Date
January 24, 2014
Primary Completion Date
December 20, 2016
Study Completion Date
February 28, 2017
PfRAS
Radiation-attenuated Plasmodium falciparum sporozoites (PfRAS) administered by the bite of infected Anopheles stephensi mosquitoes
Placebo
Administered by the bite of noninfected Anopheles stephensi mosquitoes
Challenge
5 infectious Anopheles stephensi mosquito bites carrying infectious Plasmodium falciparum sporozoites within a controlled clinical environment.
Naval Medical Research Center Clinical Trials Center (CTC), Bethesda
Seattle Children's Hospital
OTHER
Bill and Melinda Gates Foundation
OTHER
U.S. Army Medical Research and Development Command
FED