Comparison of Depression Identification After Acute Coronary Syndrome: Quality of Life and Cost Outcomes

NACompletedINTERVENTIONAL
Enrollment

1,501

Participants

Timeline

Start Date

November 30, 2013

Primary Completion Date

July 31, 2018

Study Completion Date

July 31, 2019

Conditions
Acute Coronary SyndromeDepressive Symptoms
Interventions
OTHER

Cognitive Behavioral Therapy (CBT)

"The main intervention is the impact of screening on quality of life and health care costs. CBT is provided only if depressive symptoms are detected and participant prefers this type of treatment.~CBT will be centrally telephone-administered by a trained CBT treatment specialist. The treatment specialist will work with local team members throughout a participant's involvement in the study, and will closely follow each participant until he or she has reached a requisite level of improvement ."

DRUG

Antidepressant Medication

"The main intervention is the impact of screening on quality of life and health care costs. Antidepressant Medication is provided only if depressive symptoms are detected and patient prefers this type of treatment.~Antidepressants should be started at the lowest dose, but should be adjusted upward to be within the therapeutic range within 1 week, with further adjustment higher in the therapeutic range possible at 3-4 weeks. Dosage of the first medication selected will be in the therapeutic range by 3 weeks of the initial step, as tolerated."

OTHER

Standard Care

Participants will receive standard care from either their primary care provider (PCP), or PCP-referred mental health provider in one of the arms, IF depressive symptoms are detected.

OTHER

Depressive symptom screener

8-item Patient Health Questionnaire, PHQ-8

OTHER

No intervention

Trial Locations (4)

10032

Columbia University Irving Medical Center, New York

27536

Duke University, Henderson

55440

Health Partners institute for Research and Education, Bloomington

97227

Kaiser Foundation Research Institute, Portland

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

collaborator

Duke University

OTHER

collaborator

HealthPartners Institute

OTHER

collaborator

Kaiser Foundation Research Institute

OTHER

lead

Columbia University

OTHER