1,501
Participants
Start Date
November 30, 2013
Primary Completion Date
July 31, 2018
Study Completion Date
July 31, 2019
Cognitive Behavioral Therapy (CBT)
"The main intervention is the impact of screening on quality of life and health care costs. CBT is provided only if depressive symptoms are detected and participant prefers this type of treatment.~CBT will be centrally telephone-administered by a trained CBT treatment specialist. The treatment specialist will work with local team members throughout a participant's involvement in the study, and will closely follow each participant until he or she has reached a requisite level of improvement ."
Antidepressant Medication
"The main intervention is the impact of screening on quality of life and health care costs. Antidepressant Medication is provided only if depressive symptoms are detected and patient prefers this type of treatment.~Antidepressants should be started at the lowest dose, but should be adjusted upward to be within the therapeutic range within 1 week, with further adjustment higher in the therapeutic range possible at 3-4 weeks. Dosage of the first medication selected will be in the therapeutic range by 3 weeks of the initial step, as tolerated."
Standard Care
Participants will receive standard care from either their primary care provider (PCP), or PCP-referred mental health provider in one of the arms, IF depressive symptoms are detected.
Depressive symptom screener
8-item Patient Health Questionnaire, PHQ-8
No intervention
Columbia University Irving Medical Center, New York
Duke University, Henderson
Health Partners institute for Research and Education, Bloomington
Kaiser Foundation Research Institute, Portland
Collaborators (1)
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Duke University
OTHER
HealthPartners Institute
OTHER
Kaiser Foundation Research Institute
OTHER
Columbia University
OTHER