A Study to Evaluate the Irritation Potential of GSK2894512 Cream on Skin in Healthy Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

October 30, 2013

Primary Completion Date

July 2, 2014

Study Completion Date

July 2, 2014

Conditions
Psoriasis
Interventions
DRUG

GSK2894512 cream

GSK2894512 is a white to off-white cream that will be applied topically in 3 different concentrations (0.5% \[5 milligram (mg)/gram (g)\], 1% \[10 mg/g\], and 2% \[20 mg/g\]).

DRUG

Vehicle cream

Vehicle cream does not contain any active pharmaceutical ingredient.

DRUG

Positive control

Positive control contains sodium lauryl sulfate solution 0.1% (1 mg/g).

DRUG

Negative control

Negative control contains petrolatum.

Trial Locations (2)

20095

GSK Investigational Site, Hamburg

21225

GSK Investigational Site, Baltimore

All Listed Sponsors
lead

Stiefel, a GSK Company

INDUSTRY

NCT01984775 - A Study to Evaluate the Irritation Potential of GSK2894512 Cream on Skin in Healthy Subjects | Biotech Hunter | Biotech Hunter