LGX818 for Patients With BRAFV600 Mutated Tumors

PHASE2TerminatedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

January 14, 2014

Primary Completion Date

September 1, 2015

Study Completion Date

October 13, 2015

Conditions
Solid TumorHematologic Malignancies
Interventions
DRUG

LGX818

LGX818 will be dosed on a flat scale of 300 mg (e.g., 3 x 100 mg capsules) once daily on a continuous dosing cycle. A complete treatment cycle is defined as 28 days. There will be no breaks between dosing cycles.

Trial Locations (13)

19104

University of Pennsylvania Presbyterian Medical Center University of Pennsylvania, Philadelphia

22601

Shenandoah Oncology Shenadoah Oncology (2), Winchester

33901

Florida Cancer Specialists Florida Cancer Specialists (31, Fort Myers

35211

Alabama Oncology St. Vincent's Birmingham, Birmingham

43701

Genesis Cancer Services, Zanesville

57104

Sanford Research Sanford Health, Sioux Falls

60611

Lurie Children's Hospital of Chicago Developmental Therapeutics, Chicago

72703

Highlands Oncology Group Highlands Oncology Group (22), Fayetteville

77024

Oncology Consultants Oncology Group, Houston

84106

Utah Cancer Specialists Utah Cancer Specialists (11), Salt Lake City

89109

Comprehensive Cancer Centers of Nevada CCC of Nevada (1), Las Vegas

06520

Yale University School of Medicine Smilow Cancer Hospital, New Haven

06856

Whittingham Cancer Center Norwalk Hospital, Norwalk

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT01981187 - LGX818 for Patients With BRAFV600 Mutated Tumors | Biotech Hunter | Biotech Hunter