168
Participants
Start Date
December 30, 2013
Primary Completion Date
March 11, 2019
Study Completion Date
January 9, 2020
Rogaratinib (BAY1163877) oral solution
Participants received Rogaratinib oral solution as a single dose on Cycle 1 Day 1 (C1D1) and twice daily (BID) from Cycle 1 Day 3 (C1D3) onward for the remaining 19 days of Cycle 1. For subsequent cycles, study drug was administered twice daily for 21 days each Cycle.
Rogaratinib (BAY1163877) oral tablet
Participants received Rogaratinib oral tablet as a single dose on C1D1 and BID from C1D3 onward for the remaining 19 days of Cycle 1. For subsequent cycles, study drug was administered twice daily for 21 days each Cycle.
Rogaratinib (BAY1163877) 800 mg BID
Participants received Rogaratinib 800 mg oral tablet as a single dose on C1D1 and BID (in total 1600 mg) from C1D3 onward for the remaining 19 days of Cycle 1. For subsequent cycles, study drug was administered twice daily for 21 days each Cycle.
Geneva
Chur
Sankt Gallen
Pittsburgh
Hamburg
Dijon
Besançon
Madrid
Madrid
Magdeburg
Essen
Valencia
Cologne
Lille
Lyon
Heidelberg
Tübingen
Weiden
Créteil
Würzburg
Singapore
Singapore
Chicago
Chicago
Dresden
Seoul
Seoul
Seoul
Barcelona
Lead Sponsor
Bayer
INDUSTRY