NCT01973140 - Effects of Tolvaptan in Healthy Adults | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 30, 2013

Primary Completion Date

December 31, 2015

Study Completion Date

March 31, 2016

Conditions

Healthy

Interventions

DRUG

Tolvaptan

Adult male volunteers will be given a given a 60mg or a 30 mg dose of tolvaptan. Blood and urine samples will be collected at specified time points for the next 24 hours.

DRUG

Hypertonic saline infusion

A week after the first intervention(tolvaptan), the subjects will undergo a hypertonic saline infusion for 6 hours. Blood and urine samples will be collected at specified time points until 4hour hours after the infusion.

Trial Locations (1)

60611

Clinical Research Unit Northwestern Memorial Hospital, Chicago