Renal Denervation in Patients With Uncontrolled Hypertension - SYMPLICITY HTN-4

Subjects randomized to the renal denervation group underwent angiography and renal denervation.

Prior to enrollment closure, subjects were treated with sham renal denervation. After enrollment closure, subjects previously enrolled were no longer eligible to cross-over.

Subjects who met all criteria after the screening period did undergo a renal artery angiogram to evaluate renal artery anatomy. Only subjects with eligible renal artery anatomy were randomized.