Biomarkers of Anti-TNF Treatment in Inflammatory Bowel Disease (IBD)

CompletedOBSERVATIONAL
Enrollment

45

Participants

Timeline

Start Date

October 31, 2013

Primary Completion Date

October 30, 2016

Study Completion Date

January 30, 2017

Conditions
Inflammatory Bowel Diseases
Interventions
BIOLOGICAL

Infliximab

Remission induction in anti-TNF naïve patients will be achieved by administration of 5 mg/kg IFX infusions at week 0, 2 and 6.

BIOLOGICAL

Adalimumab

ADA is administered as subcutaneous injections every other week.In children (age below 18 years), remission induction in anti-TNF naïve patients will be achieved by an initial loading dose of 80 mg, followed by 40 mg 2 weeks later. In adults, remission is induced by 160 mg at week 0, followed by 80 mg at week 2

Trial Locations (1)

3015 GJ

Erasmus Medical Center, Rotterdam

Sponsors
All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Erasmus Medical Center

OTHER

NCT01971970 - Biomarkers of Anti-TNF Treatment in Inflammatory Bowel Disease (IBD) | Biotech Hunter | Biotech Hunter