Primary Prevention of Patients With Hepatocellular Carcinoma and Concomitant Esophageal Varices

PHASE4RecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

August 31, 2009

Primary Completion Date

December 25, 2023

Study Completion Date

December 31, 2025

Conditions
Bleeding Esophageal VaricesHepatocellular Carcinoma
Interventions
DRUG

Propranolol

Propranolol 10mg BID initially and titrate dosage every week to achieve 25% drop of heart rate (keep heart rate\>55 or systemic blood pressure\>90mmHg)

PROCEDURE

Esophageal variceal ligation

Esophageal variceal ligation every 3-4 weeks to achieve variceal eradication under endoscopy

Trial Locations (1)

11217

RECRUITING

Taipei Veterans General Hospital, Taipei

All Listed Sponsors
lead

Taipei Veterans General Hospital, Taiwan

OTHER_GOV