Effects of Nalmefene After Single Dose on the Blood Oxygen Level Dependent (BOLD) fMRI Signal in the Ventral Striatum to Reward Responding in the Monetary Incentive Delay Task (MIDT), in Non-treatment Seeking Subjects With Alcohol Dependence Following Alcohol Challenge

PHASE1CompletedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

November 30, 2013

Primary Completion Date

October 31, 2014

Conditions
Alcohol Dependence
Interventions
DRUG

Nalmefene 18 mg, then placebo

One single oral dose Nalmefene on Day 1 and Placebo on Day 8

DRUG

Placebo, then Nalmefene 18 mg

One single oral dose Placebo on Day 1 and Nalmefene on Day 8

Trial Locations (1)

NW10 7EW

GB801, London

All Listed Sponsors
lead

H. Lundbeck A/S

INDUSTRY

NCT01969617 - Effects of Nalmefene After Single Dose on the Blood Oxygen Level Dependent (BOLD) fMRI Signal in the Ventral Striatum to Reward Responding in the Monetary Incentive Delay Task (MIDT), in Non-treatment Seeking Subjects With Alcohol Dependence Following Alcohol Challenge | Biotech Hunter | Biotech Hunter