Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products

NACompletedINTERVENTIONAL
Enrollment

81

Participants

Timeline

Start Date

November 3, 2013

Primary Completion Date

May 31, 2021

Study Completion Date

May 31, 2021

Conditions
Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter
Interventions
OTHER

Cigarette, NIDA test type with 16.6 mg nicotine

Smoke a single cigarette for up to 10 minutes

OTHER

Cigarette, NIDA test type with <0.45 mg nicotine

Smoke a single low-nicotine cigarette for up to 10 minutes

OTHER

Electronic cigarette with 18 mg/ml nicotine

Use electronic cigarette with 18 mg/ml nicotine for 30 minutes

OTHER

Electronic Cigarette with no nicotine

Use electronic cigarette with no nicotine for 30 minutes

OTHER

Moist snuff

Use moist snuff for 30 minutes

OTHER

Sham Smoking

Sham smoking or e-cigarette use consists of puffing on a drinking straw for 10 minutes

OTHER

Secondhand cigarette smoke (SHS)

180-minute exposure to SHS generated by controlled dilution of smoke from machine-smoked cigarettes

OTHER

Conditioned, filtered air

Exposure to conditioned, filtered air for 180 minutes

OTHER

Sham Moist Snuff

Chew gum for 30 minutes

Trial Locations (1)

94143

University of California, San Francisco, San Francisco

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

Food and Drug Administration (FDA)

FED

lead

University of California, San Francisco

OTHER

NCT01964807 - Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products | Biotech Hunter | Biotech Hunter