NCT01964495 - Reduction of Antibiotic Therapy by Biomakers in Patients With CAP Episodes (REDUCE Study) | Biotech Hunter

Enrollment

468

Participants

Timeline

Start Date

December 5, 2013

Primary Completion Date

January 20, 2017

Study Completion Date

January 20, 2017

Conditions

Community Acquired Pneumonia

Interventions

DRUG

Discontinuation of treatment according to CRP levels

The cutoff point is a CRP below 100 mg/L and a reduction to 50% of the initial value.

DRUG

Discontinuation of treatment according to PCT levels

The cutoff point is a PCT below 0.25 mcg/L or a reduction to 10% of the initial value.

DRUG

Treatment according to current guidelines

Often a 7 days course of antibiotics, treatment may be extended if the attending physician deems it necessary.

Trial Locations (3)

Medical Centre Alkmaar, Alkmaar

Slotervaart Hospital, Amsterdam

ISALA clinics, Zwolle