Comparison Between Radiofrequency Ablation and Hypofractionated Proton Beam Radiation for Recurrent/Residual HCC

NACompletedINTERVENTIONAL
Enrollment

144

Participants

Timeline

Start Date

September 30, 2013

Primary Completion Date

January 20, 2020

Study Completion Date

January 20, 2020

Conditions
Recurrent Small Hepatocellular CarcinomaResidual Small Hepatocellular Carcinoma
Interventions
PROCEDURE

radiofrequency ablation

"\* RFA(radiofrequency ablation )~* RFA electrode: Cool-tip RF ablation system (Covidien plc, 20 Lower Hatch Street Dublin 2, Ireland) and Well-Point RF Electrode (STARmed, Koea)~* performed using either the manufacturer's standard algorithm or an interactive algorithm, with the latter being used when the impedance did not begin to increase at the midinterval of the standard algorithm~* the duration of a single RFA session was 10 min to 15 min."

RADIATION

Proton beam therapy

"\* Proton~66 GyE /10 fx, 6.6 GyE fraction dose, 5 days/week, for HCC free from the alimentary tract (i.e., stomach, duodenum, esophagus, small and large bowel) (more than 2cm from clinical target volume),TLV30\<40%,and/orRLV30\<30%)"

Trial Locations (1)

410-769

National Cancer Center, Korea, Goyang-si

All Listed Sponsors
lead

National Cancer Center, Korea

OTHER_GOV

NCT01963429 - Comparison Between Radiofrequency Ablation and Hypofractionated Proton Beam Radiation for Recurrent/Residual HCC | Biotech Hunter | Biotech Hunter