SOF (Sovaldi®) +RBV for 16 or 24 Weeks and SOF+RBV+Peg-IFN for 12 Weeks in Adults With Genotype 2 or 3 Chronic HCV Infection

PHASE3CompletedINTERVENTIONAL
Enrollment

601

Participants

Timeline

Start Date

September 24, 2013

Primary Completion Date

January 7, 2015

Study Completion Date

July 7, 2016

Conditions
Hepatitis C
Interventions
DRUG

SOF

400 mg tablet administered orally once daily

DRUG

RBV

Tablets administered orally in a divided daily dose according to package insert weight-based dosing recommendations (\< 75 kg = 1000 mg and ≥ 75 kg = 1200 mg)

DRUG

Peg-IFN

180 µg administered via subcutaneous injection once weekly

Trial Locations (78)

1010

Grafton

1023

Grafton

2050

Camperdown

2145

Westmead

2217

Kogarah

3004

Melbourne

3065

Fitzroy

3084

Heidelberg

3168

Clayton

3204

Hamilton

4029

Brisbane

4102

Woolloongabba

4120

Greenslopes

5000

Adelaide

6009

Nedlands Perth

6021

Wellington

8011

Christchurch

10021

New York

13903

Binghamton

23502

Norfolk

30060

Marietta

33136

Miami

33414

Wellington

37211

Nashville

38138

Germantown

48377

Novi

55114

Saint Paul

70121

New Orleans

76012

Arlington

78705

Austin

80045

Aurora

80113

Englewood

92123

San Diego

92501

Riverside

94115

San Francisco

98101

Seattle

02215

Boston

08844

Hillsborough

07102

Newark

37212-1610

Nashville

T2N 4Z6

Calgary

T6G 2B7

Edmonton

V5Z 1M9

Vancouver

V6Z 2C7

Vancouver

V6Z 2K5

Vancouver

R3E 3P4

Winnipeg

L8N 4A6

Hamilton

N6A 5A5

London

K1H 8L6

Ottawa

M5T 2S8

Toronto

M6H 3M1

Toronto

H2X 3J4

Montreal

G1V 4G2

Québec

B15 2TH

Edgbaston

CB2 0QQ

Cambridge

E1 1BB

London

SE5 9RS

London

SW17 ORE

London

W2 1NY

London

B9 5SS

Birmingham

BD9 6RJ

Bradford

DD1 9SY

Dundee

EH16 4SA

Edinburgh

EH4 2XU

Edinburgh

GU46 6HU

Frimley

G12 0YN

Glasgow

G4 0SF

Glasgow

LS9 7TF

Leeds

L7 8XP

Liverpool

NW3 2QG

London

SW10 9NH

London

M85RB

Manchester

NE7 7DN

Newcastle upon Tyne

NG7 2UH

Nottingham

OX3 9DU

Oxford

PL6 8DH

Plymouth

PO6 3LY

Portsmouth

SO16 6YD

Southampton

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Gilead Sciences

INDUSTRY