Combined Treatment for Mixed Incontinence

PHASE3CompletedINTERVENTIONAL
Enrollment

480

Participants

Timeline

Start Date

October 28, 2013

Primary Completion Date

August 9, 2017

Study Completion Date

September 29, 2017

Conditions
Urinary Incontinence, StressUrinary Incontinence, Urge
Interventions
PROCEDURE

Miduretheral Sling

MUS can include the TVT™ (mechanical cut mesh only, Gynecare, ETHICON Women's Health \& Urology, Somerville, NJ), TVT-O™ (mechanical cut mesh only, Gynecare), or Monarc™ (American Medical Systems, Minnetonka, MN).

OTHER

Miduretheral Sling with behavioral/pelvic floor therapy

MUS is combined with components of behavioral therapy (designed to change behaviors to encourage continence), and pelvic floor muscle therapy (designed to strengthen the pelvic floor muscles, enhance the physiological closure of the bladder neck, and improve coordination). This is done prior to MUS (1 visit) and after MUS for 5 visits at 2, 4, 6, 8 weeks and 6 months.

Trial Locations (10)

15213

Magee-Womens Hospital, Department of Obstetrics and Gynecology, Pittsburgh

19104

University of Pennsylvania, Philadelphia

27707

Duke University, Duke Division of Urogynecology and Reconstructive Pelvic Surgery, Durham

44195

Cleveland Clinic, Department OB/GYN, Cleveland

90242

Kaiser Permanente -- Downey, Downey

92110

Kaiser Permanente -- San Diego, San Diego

35249-7333

University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Birmingham

92037-0974

University of California at San Diego, UCSD Women's Pelvic Medicine Center, La Jolla

87131-0001

University of New Mexico Health Sciences Center, Department of Obstetrics and Gynecology, Albuquerque

02903

Brown/ Women and Infants Hospital of Rhode Island, Center for Women's Pelvic Medicine and Reconstructive Surgery, Providence

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Women and Infants Hospital of Rhode Island

OTHER

collaborator

The Cleveland Clinic

OTHER

collaborator

Duke University

OTHER

collaborator

University of Alabama at Birmingham

OTHER

collaborator

University of New Mexico

OTHER

collaborator

University of Pennsylvania

OTHER

collaborator

University of Pittsburgh

OTHER

collaborator

University of California, San Diego

OTHER

collaborator

Kaiser Permanente

OTHER

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

RTI International

OTHER

lead

NICHD Pelvic Floor Disorders Network

NETWORK

NCT01959347 - Combined Treatment for Mixed Incontinence | Biotech Hunter | Biotech Hunter