Botulinum Toxin Injection in Hypercontractile Esophagus

PHASE2CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

August 31, 2013

Primary Completion Date

May 31, 2017

Study Completion Date

February 28, 2018

Conditions
Nutcracker Oesophagus
Interventions
DRUG

Esophageal endoscopic injection of botulinum toxin

Endoscopic injection of botulinum toxin in the esophageal muscle : one hundred units of type A botulinum toxin (Botox®, Allergan) diluted in 10 mL of normal saline and injected at the lower third of the esophageal wall in 10 sites between 2 and 10 cm above the Z-line.

OTHER

No injection of botulinum toxin

Upper gastro-intestinal endoscopy without any injection

Trial Locations (2)

33075

Service d'Hépato-Gastro-Entérologie et Oncologie Digestive- Hôpital Haut Lévêque - CHU de Bordeaux, Bordeaux

69437

Service d'Exploration Fonctionnelle Digestive - Hôpital Edouard Herriot Pavillon H 5 - Hospices Civils de Lyon, Lyon

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER

NCT01955174 - Botulinum Toxin Injection in Hypercontractile Esophagus | Biotech Hunter | Biotech Hunter