Start Date
April 30, 2014
Primary Completion Date
November 30, 2016
Study Completion Date
November 30, 2016
Vintafolide 2.5 mg
During treatment, participants receive IV vintafolide 2.5 mg.
Paclitaxel 80 mg/m^2
During treatment, participants receive IV paclitaxel 80 mg/m\^2.
Etarfolatide
During screening and prior to screening CT scan, participants receive an IV injection of 0.1 mg etarfolatide radiolabeled with 20 to 25 milliCuries of technetium-99m.
Folic acid
During screening and prior to etarfolatide injection and screening CT scan, participants receive an IV injection of 0.5 mg folic acid.
Premedication for Paclitaxel
During treatment, participants receive dexamethasone 20 mg orally 12 to 6 hours prior to paclitaxel; OR promethazine 25 mg or 50 mg IV 30 to 60 minutes prior to paclitaxel; OR cimetidine 300 mg IV or ranitidine 50 mg IV 30 to 60 minutes prior to paclitaxel.
Lead Sponsor
Endocyte
INDUSTRY