A Phase 1 Study in Patients With Relapsed or Refractory Hodgkin Lymphoma or Systemic Anaplastic Large Cell Lymphoma

PHASE1CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

November 30, 2013

Primary Completion Date

October 31, 2014

Study Completion Date

June 30, 2015

Conditions
Hodgkin LymphomaAnaplastic Large-cell Lymphoma
Interventions
DRUG

brentuximab vedotin

Brentuximab vedotin will be administered every 3 weeks at a dose of 1.8 mg/kg.

DRUG

Brentuximab vedotin and rifampicin

Brentuximab vedotin will be administered every 3 weeks at a dose of 1.8 mg/kg beginning on Cycle 1, Day 1; daily rifampicin (600 mg PO) will be administered during Cycles 0 through 3 only, beginning on Cycle 0, Day 1 (7 days before the Cycle 1, Day 1 dose of brentuximab vedotin) and continuing through Cycle 3, Day 21.

Trial Locations (6)

Unknown

Brussels

Ghent

Vilnius

Barcelona

Madrid

Salamanca

All Listed Sponsors
lead

Millennium Pharmaceuticals, Inc.

INDUSTRY

NCT01950364 - A Phase 1 Study in Patients With Relapsed or Refractory Hodgkin Lymphoma or Systemic Anaplastic Large Cell Lymphoma | Biotech Hunter | Biotech Hunter