176
Participants
Start Date
January 31, 2014
Primary Completion Date
December 8, 2016
Study Completion Date
December 8, 2016
LDMTX
"LDMTX 5 mg: one 5-mg capsule by mouth once weekly~LDMTX 10 mg: two 5-mg capsules by mouth once weekly~LDMTX 15 mg: three 5-mg capsules by mouth once weekly"
Placebo
"Placebo 5 mg: one 5-mg capsule by mouth once weekly~Placebo 10 mg: two 5-mg capsules by mouth once weekly~Placebo 15 mg: three 5-mg capsules by mouth once weekly"
Folic acid
1-mg tablet of folic acid by mouth once a day
University of Pittsburgh CRS, Pittsburgh
Penn Therapeutics, CRS, Philadelphia
Johns Hopkins University CRS, Baltimore
Greensboro CRS, Greensboro
Chapel Hill CRS, Chapel Hill
Alabama CRS, Birmingham
Vanderbilt Therapeutics (VT) CRS, Nashville
Ohio State University CRS, Columbus
Case Clinical Research Site, Cleveland
Cincinnati Clinical Research Site, Cincinnati
Northwestern University CRS, Chicago
Houston AIDS Research Team CRS, Houston
University of Colorado Hospital CRS, Aurora
UCLA CARE Center CRS, Los Angeles
Harbor-UCLA CRS, Torrance
UCSD Antiviral Research Center CRS, San Diego
Ucsf Hiv/Aids Crs, San Francisco
University of Southern California CRS, Los Angeles
Brigham and Women's Hospital Therapeutics Clinical Research Site (BWH TCRS) CRS, Boston
Washington University Therapeutics (WT) CRS, St Louis
New Jersey Medical School Clinical Research Center CRS, Newark
The Miriam Hospital Clinical Research Site (TMH CRS) CRS, Providence
National Institute of Allergy and Infectious Diseases (NIAID)
NIH