Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders

NACompletedINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

November 17, 2014

Primary Completion Date

June 1, 2018

Study Completion Date

December 31, 2018

Conditions
Major Depressive DisorderPersistent Depressive DisorderPosttraumatic Stress DisorderPanic DisorderSocial PhobiaSpecific PhobiaGeneralized Anxiety DisorderObsessive Compulsive Disorder
Interventions
BEHAVIORAL

Transdiagnostic Behavior Therapy

A new transdiagnostic CBT protocol for the depressive/anxiety disorders was developed and revised through two demonstration studies and one focus group. The resulting protocol involves several primary components, including psychoeducation on the symptoms of depression and anxiety (session 1), assessment of motivation and setup of treatment plans (session 2), exposure therapy (sessions 3-15), and relapse prevention (final session). In addition to these primary components, optional modules are included to supplement exposure therapy later in treatment to address secondary symptoms (e.g., anger, sleep, hypervigilance, drinking to cope). The goal of these modules is to allow providers to tailor treatment to specific symptoms that may be present in any single or set of diagnoses that may be reducing the effects from the primary exposure approach. Session will be weekly for 45-60 minutes with homework assignments to be completed between sessions.

BEHAVIORAL

Behavioral Activation Therapy

To provide an evidence-based comparison for the transdiagnostic CBT condition, a second group of participants will receive manualized BAT. In general, BAT involves teaching patients to monitor their mood and daily activities with the goal of increasing pleasant, reinforcing activities and reducing unpleasant events. In the present study, the BAT condition will be manualized, following an existing protocol in the literature. BAT will be structurally equivalent to the transdiagnostic CBT with the same session length (45-60 minutes), frequency of sessions (weekly), duration of treatment (12-16 sessions), and amount of homework.

Trial Locations (1)

29401-5799

Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston

All Listed Sponsors
lead

VA Office of Research and Development

FED

NCT01947647 - Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders | Biotech Hunter | Biotech Hunter