Predictive Value of the Immune Response of the Host in Clostridium Difficile Infections

NACompletedINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

December 31, 2012

Primary Completion Date

June 30, 2016

Study Completion Date

June 30, 2017

Conditions
Clostridium Difficile Infection
Interventions
BIOLOGICAL

Serum

BIOLOGICAL

Stools

BIOLOGICAL

Saliva

Optional sample collected for the cases and non-diarrheal control at the same time as the serum, to compare the presence of specific salivary Immune globulin type A (IgA) of C. difficile antibodies than in the serum.

BIOLOGICAL

Whole blood

Optional sample collected for the cases and non-diarrheal control at the same time as the serum, in order to study cellular immunity and describe the determinants of the development of a protective adaptive response.

Trial Locations (24)

Unknown

CH Annecy Genevois, Annecy

Hôpital Jean Verdier, Bondy

Hôpital Ambroise Paré, Boulogne-Billancourt

Hôpital Côte de Nacre, Caen

Hôpital Antoine Béclère, Clamart

CHU de Dijon - Hôpital d'Enfants, Dijon

Hôpital Raymond Poincaré, Garches

CHU de Grenoble, Grenoble

CHD Vendée, La Roche-sur-Yon

CHRU de Montpellier - Hôpital Arnaud de Villeneuve, Montpellier

Hôpital Central de Nancy, Nancy

Fondation Hospitalière Sainte-Marie, Paris

Groupe Hospitalier Paris Saint Joseph, Paris

Groupe Hospitalier Sainte-Périne / Rossini / Chardon Lagache, Paris

Hôpital Lariboisière, Paris

Hôpital Saint Antoine, Paris

CHU de Reims - Hôpital Robert Debré, Reims

CHU de Rennes - Hôpital Pontchaillou, Rennes

CHU de Rouen - Hôpital Charles Nicolle, Rouen

CHU de Toulouse - Hôpital Purpan, Toulouse

CH de Tourcoing - Hôpital Gustave Dron, Tourcoing

CHRU de Tours - Hôpital Bretonneau, Tours

CH de Valenciennes, Valenciennes

Centre Hospitalier de Versailles, Versailles

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Institut Pasteur

INDUSTRY

collaborator

Sanofi Pasteur, a Sanofi Company

INDUSTRY

collaborator

Saint Antoine University Hospital

OTHER

lead

Versailles Hospital

OTHER

NCT01946750 - Predictive Value of the Immune Response of the Host in Clostridium Difficile Infections | Biotech Hunter | Biotech Hunter