Sodium-Restricted Diet and Diuretic in the Treatment of Severe Sleep Apnea

PHASE4CompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

October 31, 2013

Primary Completion Date

February 28, 2015

Study Completion Date

February 28, 2015

Conditions
Obstructive Sleep Apnea
Interventions
DRUG

Lasilactone

Active drug (spironolactone 100 mg plus furosemide 20 mg).

OTHER

Sodium-Restricted Diet

The sodium-restricted diet will enforce some rules: do not use salt in cooking; do not use the salt shaker; do not ingest any industrialized food; to eat fresh salads and vegetables; do not add high-sodium seasonings, among others. The complete dietary rules will be delivered to each volunteer in a four page handout.

DRUG

Placebo

The placebo group will receive cellulose-based placebo pills with identical pills and flasks to active drug.

Trial Locations (1)

90035-903

Hospital de Clinicas de Porto Alegre, Porto Alegre

All Listed Sponsors
lead

Hospital de Clinicas de Porto Alegre

OTHER

NCT01945801 - Sodium-Restricted Diet and Diuretic in the Treatment of Severe Sleep Apnea | Biotech Hunter | Biotech Hunter