Phase II Safety and Efficacy Study of Crizotinib in East Asian Patients With ROS1 Positive, ALK Negative Advanced NSCLC

PHASE2CompletedINTERVENTIONAL
Enrollment

129

Participants

Timeline

Start Date

September 30, 2013

Primary Completion Date

July 31, 2015

Study Completion Date

January 22, 2020

Conditions
Non Small Cell Lung CancerROS1 Proto OncogeneCrizotinib
Interventions
DRUG

Crizotinib

Trial Locations (44)

100021

Department of Medical Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Chaoyang District

100071

307 Hospital of PLA/Department of Lung Cancer, Fengtai District

100142

Beijing Cancer Hospital, Department of Thoracic Oncology, Haidian District

100700

The Military General Hospital of Beijing PLA / Medical Oncology Dept., Dongcheng District

100853

Chinese PLA General Hospital, Haidian District

200030

Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai

Shanghai Chest Hospital/Lung cancer clinical center, Shanghai

200032

Zhongshan Hospital Fudan University / Respiratory Department, Xuhui District

200433

Shanghai Pulmonary Hospital, Shanghai

230022

The First Affiliated Hospital of Anhui Medical University, Department of Medical Oncology, Hefei

266101

The affiliated hospital of medical college Qingdao University / Medical oncology department, Qingdao

300060

Department of Thoracic Oncology, Tianjin Medical University Cancer Institute and Hospital, Hexi District

310003

The First Affiliated Hospital of College of Medicine, Zhejiang University, Hangzhou

310016

Sir Run Run Shaw Hospital of College of Medicine of Zhejiang University, Center for Oncology, Hangzhou

350014

Fujian Province Oncology Hospital, Fuzhou

400038

Respiration department,the First Affiliated Hospital of Third Military Medical University, PLA, Shapingba District

410013

Hunan Provincial Tumor Hospital/Division of Oncology, Changsha

510060

SUN Yat-Sen University Cancer Center, Guangzhou

510120

The First Affiliated Hospital of Guangzhou Medical College, Guangzhou

610041

Oncology Department, West China Hospital of Sichuan University, Chengdu

Sichuan Province Cancer Hospital/Department of Pulmonary Tumor, Chengdu

Unknown

Beijing Chest Hospital, Tongzhou District

Guangdong General Hospital, Guangzhou

Department of Oncology, Jilin Provincial Cancer Hospital, Changchun

Zhejiang Cancer Hospital, Hangzhou

Aichi Cancer Center Hospital, Aichi

National Cancer Center Hospital East, Chiba

NHO Shikoku Cancer Center, Ehime

NHO Kyushu Cancer Center, Fukuoka

Hyogo Cancer Center, Hyōgo

Tohoku University Hospital, Miyagi

Kinki University Hospital, Osaka

Osaka City General Hospital, Osaka

Cancer Institute Hospital of JFCR, Tokyo

National Cancer Center Hospital, Tokyo

Asan Medical Center, Seoul

Samsung Medical Center, Seoul

Seoul National University Hospital, Seoul

Yonsei University, Severance Hospital, Seoul

Taichung Veterans General Hospital, Taichung

National Cheng Kung University Hospital, Tainan City

National Taiwan University Hospital, Taipei

Taipei Veterans General Hospital, Taipei

411-8777

Shizuoka Cancer Center, Sunto-gun

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

OxOnc Development LP

OTHER

lead

Pfizer

INDUSTRY

NCT01945021 - Phase II Safety and Efficacy Study of Crizotinib in East Asian Patients With ROS1 Positive, ALK Negative Advanced NSCLC | Biotech Hunter | Biotech Hunter