Safety and Efficacy of GS-4774 for the Treatment of Chronic Hepatitis B

PHASE2CompletedINTERVENTIONAL
Enrollment

178

Participants

Timeline

Start Date

September 13, 2013

Primary Completion Date

September 9, 2014

Study Completion Date

March 3, 2015

Conditions
Chronic HBV Infection
Interventions
BIOLOGICAL

GS-4774

Administered as a subcutaneous injection every 4 weeks for a total of 6 doses

DRUG

OAV Regimen

Administered prior to study enrollment (tenofovir disoproxil fumarate, entecavir, adefovir, lamivudine, or telbivudine either as single agents or in combination)

Trial Locations (17)

1141

Auckland Clinical Studies, Grafton

11030

North Shore LIJ Health System, Manhasset

11355

Medical Pro-care, Flushing

21229

Digestive Disease Associates, PA, Baltimore

23602

Bon Secours St. Mary's Hospital of Richmond, Newport News

33136

University of Miami, Miami

48109

University of Michigan, Ann Arbor

48202

Henry Ford Hospital and Health System, Detroit

60611

Northwestern Memorial Hospital, Chicago

63104

St.Louis University, St Louis

90095

Dumont-UCLA Liver Transplant Center, Los Angeles

91105

Huntington Medical Research Institutes, Pasadena

92154

Kaiser Permanente, San Diego

94118

Kaiser Permanente, San Francisco

95128

Silicon Valley Research Institute, San Jose

95825

Kaiser Permanente, Sacramento

02111

Tufts Medical Center, Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Gilead Sciences

INDUSTRY

NCT01943799 - Safety and Efficacy of GS-4774 for the Treatment of Chronic Hepatitis B | Biotech Hunter | Biotech Hunter