Prospective, Randomized, Multicentre, Open-label, Phase II / III Study to Assess Efficacy and Safety of Ranibizumab 0.5 mg Intravitreal Injections Plus Panretinal Photocoagulation (PRP) Versus PRP in Monotherapy in the Treatment of Subjects With High Risk Proliferative Diabetic Retinopathy.

Department of Ophthalmology, University Vita Salute - Scientific Institute of San Raffael, Milan

Department of Ophthalmology, University Hospital, CHU Dijon, Dijon

Centre for Clinical Trials, Department of Ophthalmology, University of Padova, Padua

Department of Ophthalmology, Lariboisière Hospital, Paris

Centre d'Investigation Clinique - Centre National d'Ophtalmologie des Quinze-Vingts, Paris

G.B.Bietti Eye Foundation - IRCCS, Rome

Centre for Clinical Trials - Association for Innovation and Biomedical Research on Light and Image, Coimbra

Espaço Médico de Coimbra, Coimbra

Instituto de Retina de Lisboa, Lisbon

Serviço de Oftalmologia,Hospital de Vila Franca de Xira, Vila Franca de Xira

Ophthalmology Clinical Trials Unit Frimley Park Hospital Foundation Trust, Frimley

Clinical Trial Unit, Dep. Ophth., Gloucestershire Hospitals NHS Foundation Trust, Gloucestershire

Laser and Retinal Research Unit, King's Health Partners, London