100
Participants
Start Date
November 20, 2013
Primary Completion Date
July 10, 2016
Study Completion Date
July 10, 2016
Azathioprine
Participants may receive azathioprine as a concomitant therapy with tocilizumab as per physician's judgment at a stable dose that was initiated at least 4 weeks prior to baseline.
Chloroquine
Participants may receive chloroquine as a concomitant therapy with tocilizumab as per physician's judgment at a stable dose that was initiated at least 4 weeks prior to baseline.
Hydroxychloroquine
Participants may receive hydroxychloroquine as a concomitant therapy with tocilizumab as per physician's judgment at a stable dose that was initiated at least 4 weeks prior to baseline.
Leflunomide
Participants may receive leflunomide as a concomitant therapy with tocilizumab as per physician's judgment at a stable dose that was initiated at least 4 weeks prior to baseline.
Methotrexate
Participants may receive methotrexate as a concomitant therapy with tocilizumab as per physician's judgment at a stable dose that was initiated at least 4 weeks prior to baseline.
Sulfasalazine
Participants may receive sulfasalazine as a concomitant therapy with tocilizumab as per physician's judgment at a stable dose that was initiated at least 4 weeks prior to baseline.
Tocilizumab
Participants will receive tocilizumab at a fixed dose of 162 mg SC QW either as monotherapy or in combination with non-biologic DMARDs.
Hippokratio Hospital; 2Nd Internal Medicine, Athens
District Gen. Hosp. of Athens Laiko; A Propedeutic Internal Medicine Clinic & Research Center, Athens
Laiko General Hospital; Dept. of Pathophysiology-Uni of Athens, Athens
ATTIKO Hospital_4th University Internal Medicine Clinic, Haidari
Uni General Hospital of Heraklion; Medicine and Rheumatology Clinical Immunology and Allergy Dept, Heraklion
Uni Hospital of Ioannina; Rheumatology, Ioannina
University General Hospital of Larissa; Rheumatology Unit, Larissa
University Hospital of Patras; Rheumatology, Pátrai
EUROMEDICA Geniki Kliniki Thessalonikis; Rheumatology Department, Thessaloniki
General Hospital of Thessaloniki HIPPOKRATIO; Clinical Immunology Unit,2nd Dept of Internal Medicine, Thessaloniki
Hoffmann-La Roche
INDUSTRY